This device can heal the rectum without surgery

THE ESSENTIAL

  • Three five-minute sessions combined with external radiation therapy are sufficient.
  • The risk of recurrence is 10%.
  • Rectal cancer affects more than 40,000 people in France every year.

This is a leap in the evolution of cancer treatment. One device, the Papillon 50, can treat rectal cancer without patients having to undergo surgery. It will be used at the Antoine-Lacassagne Center in Nice (Alpes-Maritimes) and will be presented and recognized at the American Society of Clinical Oncology Congress. “That realization is like sending a rocket to the moon and it reaches orbit, it’s the same feeling.”Jean-Pierre Gérard, radiotherapist at the Nice Cancer Center in Nice, said in an interview 20 protocol.

An important alternative for patients

Treatment with Papillon 50, also known as contact therapy or brachytherapy, is a potentially life-changing alternative for rectal cancer patients. To date, treatment for her condition has generally relied on abdominal surgery accompanied by chemotherapy and/or radiation therapy, but often has involved wearing a colostomy bag to collect the stool.

The technique was invented in the 1940s by Professor Papillon, based in Lyon. Jean-Pierre Gérard was one of his assistants. “The method fell into disuse in the 1990s and is an expensive piece of equipment. Philipps, who was in charge of manufacturing, quit in the 2000s.he says 20 protocol. In 2004 he started a first study to reintroduce the device, and in 2014 a second study of international scope entitled “Opera” on organ preservation in early rectal adenocarcinomas. The results were released on June 2, 2022, following the American Society of Clinical Oncology meeting. The treatment “classic‘, through chemotherapy and external beam radiation therapy, was 60% effective, treatment with the Papillon 50 eliminated the tumor in 90% of patients. Despite these encouraging results, the device is limited to a specific type of tumor: those smaller than 5 cm are in diameter.

An application in other tumors?

For Pr Gérard, however, the technology offers hope. “This machine could also be effective for eyelids, mouth, vagina and whole body on the surface. he confirms to our colleagues 20 protocol. More than 10% of all cancers in France could benefit from this technique.” So far there are only three devices of this type in France.

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