Stool transplantation has anti-aging effects in mice

A British research institute recently presented the results of a surprising study. Researchers used fecal transplants in mice of different ages to observe changes. However, according to the work, this technique would have beneficial effects on health, especially aging.

Fecal microbiota transplantation

Many people have been looking for a solution for a long time Fight against the effects of aging. In addition to creams and cosmetic surgery, research has also been dealing with the topic for several decades. For example, research had explored the hypothesis that young people’s blood might slow the effects of time in older people. In December 2021 there was also talk of an experimental anti-aging vaccine that had increased the longevity of mice.

Mice are also the focus of the research, details of which were published in the journal Microbiome on April 29, 2022. Scientists at the Quadram Institute (UK) say they have done this Transplantation of microbiota from the feces of younger mice in older mice. The aim here was to observe the possible changes at work.

Stool transplantation (or stool bacterial therapy) aims to do this restore microbial ecology and gut homeostasis. To achieve this, a healthy bacterial flora is reintroduced from the stool of a healthy donor. This technique is one of the non-pharmacological therapeutic approaches.

The transplantation of faecal microbiota can be used in particular to fight infections with the bacteria Clostridium difficile. Credit: Public domain

Very promising results

According to the test results, older mice showed improvements about her problems with bowel, eyes and brain function. In addition, the researchers also transplanted microbiota from older mice to younger mice. The latter then suddenly introduced himself various signs of aging gut and inflammation. The Quadram Institute study shows once again the important role gut microbes play in health, particularly in relation to the retina, brain and aging.

And if one day young human donor did it allow older people to fight the effects of time? We’re not there yet, but nothing seems impossible. Although the study results are very promising, more research is needed. It must be said that the stool transplant was only tested on mice and that the first human trials are not yet planned.

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