Science is looking for the “never infected” to unlock their mysteries

A New York university has launched a global study to try to unlock the genetic mysteries of people who have never been infected.

They are already 700. This number corresponds to that of people who have responded to the call from Rockefeller University in New York, which has launched an international study to see if there is genetic resistance to Covid.

In addition, 5,000 people presented themselves as having never had Covid and are being tested, reports the Swiss daily Le Matin.

3 out of 4 Americans infected

And it’s not that easy to find candidates because the Washington Post tells us that according to a model developed by the University of Washington, 76% of the citizens of the United States would have been affected. But it is also possible that you have come into contact with the virus and become infected without developing any symptoms.

To be sure, the presence of antibodies in the blood must be determined. Only the tests cannot all detect whether these antibodies are present after contamination or vaccination.

Looking for a common denominator

It is therefore necessary to uncover a common point between these participants. Because non-infection can be the result of barrier gestures, vaccinations or just luck.

And can this happiness come from genetic inheritance? Jennifer Nuzzo, an epidemiologist at Brown University School of Public Health, explains: “Studying the genes and other biological traits of people who never get the coronavirus could shed light on how the virus grows or how it infects the human body and makes people sick.”.

From the relevant recipients

According to the specialist, some people may have fewer receptors in their nose, throat and lungs, making it harder for the virus to bind. In other words, he finds it less easy to “hold on”. A person could also have been previously exposed to an equivalent infectious agent, or simply been born with an immune system that is better able to fight off or avoid these types of respiratory viruses.

So how? One idea would be to focus on people who are particularly exposed and regularly tested, and we are thinking of medical staff or top athletes who very often have had to comply in order to be able to continue their professional activity. In the event that they have always tested negative in an environment where many have been contaminated, there must be a reason other than sheer luck.

If researchers can pinpoint the causes, it will become easier to develop a targeted treatment to fight the virus.

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