What if the bacteria that live in our gut were a way to fight aging? Thatfrom a young mouse in an old mouse can reverse age-related inflammation retina and gut of corresponding . It is not the first time that a of microbiota makes it possible to “rejuvenate” mice.
The microbiota reduces age-related inflammation
In this case, the scientists first killed the recipient mice’s microbiota before giving them fecal pellets containing the microbiota of a younger or older mouse. They also analyzed markers of inflammation in the brain, retina and gut of transplanted mice. When a young mouse is transplanted with a microbiota from an older rodent, it shows inflammation characteristic of old age. Conversely, an old mouse grafted with the microbiota of a young animal will see these traits reabsorbed.
The implications of this research are still unclear, but scientists believe soof the microbiota could prevent the inflammatory problems associated with aging. More research is needed to estimate the long-term benefits on animal health and ultimately on human health.
Stool transplant rejuvenates mice
Article bypublished on August 15, 2021
In mice, transplanting a fecal microbiota from a young mouse to an old mouse appears to ‘rejuvenate’ certain abilities of that mouse.
About two kilogramslive in our digestive system, after which . Out of Bacteria, and that affect our health, including our immune and neurological functions. A new study published in suggests that this microbiome could be a relevant therapeutic target to promote healthy aging.
A find from transplants fromfeces. The donors were mice, either 3-4 months old or 19-20 months old, while the recipients were systematically 19-20 months old. Only transplants from young mice were effective. They have ” reverse aging differences However, the authors also write about some aspects of immunity cognitive impairments associated with age.
All in good time
” previous research […] have shown that theGut plays a key role in the and the aging process recalls John Cryan, co-author of the study. This new research could be a game changer, as we found that the microbiome can be harnessed to reverse age-related brain deterioration. We also see evidence of improved learning ability and cognitive function. »
These results could have important implications for theor the out of of aging. But he is ” still early ‘ John Cryan warns against projecting yourself into it Therapies: Much more work is needed to see how these results translate to humans. »