Pfizer, Moderna, Janssen, AstraZeneca: all the side effects detected for these anti-Covid vaccines

The National Medicines Safety Agency notes the top side effects of anti-Covid vaccines. It also explains what to do if you experience these symptoms.

Everything you need to know about the side effects of anti-Covid vaccines. Sixteen months after the start of the vaccination campaign in France, the National Medicines Safety Agency (ANSM) is making an inventory of the most important side effects observed.

Pfizer and Moderna vaccines: potentially dangerous rare effects

The effects of most concern are very rare, according to ANSM. These include facial paralysis or facial swelling that occurs in patients who have had facial cosmetic injections. But the ANSM also finds “inflammation of the heart muscle (myocarditis) or inflammation of the lining outside of the heart (pericarditis) that can cause shortness of breath, rapid heartbeat, or chest pain” that generally occurs “14 days after the injection.” “. In these cases, it is advisable to consult a doctor without delay.

The ANMS advises to respond immediately in case of a skin reaction with red spots or spots on the skin, an allergic reaction (hives, facial swelling, anaphylactic shock, etc.) or severe swelling of the limb vaccine. “These mild to severe effects are known, but their frequency is undetermined,” she says.

More common side effects

The most common effects are known and some are common to all vaccines. Uncomfortable, they are not serious and spontaneously disappear in a few days. The most common are: pain at the injection site with possible reactions (redness, hives, swelling), fatigue, headache, chills, fever, joint and muscle pain, diarrhea, insomnia, excessive sweating, decreased appetite, feeling weak, lack of energy, drowsiness, nausea, vomiting and rash.

“If the effect does not wear off spontaneously within a few days, consult a doctor (pharmacist or doctor), advises the ANMS. In case of fever and / or pain, we advise to favor the use of paracetamol in the lowest dose and for the shortest possible time.

The National Medicines Safety Agency (ANSM) notes other, rarer but potentially bothersome effects: pain in the extremities, swelling of the lymph nodes, malaise, dizziness, itching at the injection site, hypoesthesia (reduced touch or sensation). In case of complaints, it is also advisable to contact a medical staff.

Impairments for Moderna and Pfizer.
National Agency for Drug Safety

Janssen: the main serious effects

If their frequency is not currently determined, ANSM detects some capillary leak syndromes (CFS) and spinal cord inflammation for which prompt medical attention is advisable.

CFS is described as a “disease that causes fluid to leak out of small blood vessels.” It is a “serious condition that causes rapid swelling of the arms and legs, sudden weight gain, and a feeling of weakness (low blood pressure)”.

Less commonly, but just as dangerous, other side effects have been noted. In particular, there have been reports of Guillain-Barré Syndrome (GBS), a severe neuritis that can lead to paralysis and breathing difficulties or even immune thrombocytopenia, which leads to very low blood platelet levels. There is also the possibility of blood clots forming in unusual areas of the body such as the brain, intestines, liver or spleen. The majority of these cases occurred within the first 3 weeks after vaccination and mainly occurred in women under 60 years of age.

Adverse effects noted for Janssen.

Adverse effects noted for Janssen.
National Agency for Drug Safety

AstraZeneca: the main serious effects

Main side effect of AstraZeneca, angioedema: “Rapid swelling under the skin in areas like the face, lips, mouth, and throat can cause difficulty swallowing or breathing,” explains the ANSM. This pathology requires prompt medical treatment.

As with certain other anti-Covid vaccines, the National Medicines Safety Agency also notes rare risks of capillary leak, spinal cord inflammation, Guillain-Barré syndrome, immune thrombocytopenia and blood clot formation.

Side effects of AstraZeneca.

Side effects of AstraZeneca.
National Agency for Drug Safety

In the case of an unlisted side effect, it is possible to report it online.

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